If you don't feel like donating to me, or would like to help in a larger way (in the societal sense) you could donate (or in some other way lend support) to one of the organisations I've listed below. They are all doing work I think very highly of and are to the best of my knowlege on the up and up.
Human Rights/Issues
Amnesty International -
Doctors Without Borders - It takes a special kind of person to go into some of the most god forsaken places on Earth and try to help people. They need and deserve our support.
The EFF Homepage - The Electronic Frontier Foundation, a group that fights to preserve the right to freely share information and ideas online, which it believes to be as important as our other civil liberties.
Human Rights Watch -
MoveOn.org - Liberal web site currently working to oust President Bush. A bit radical for my tastes in some ways, but overall a great site.
Planned Parenthood - Whatever your feelings on abortion, and other reproductive health issues, these people are trying to do some good. An excellent source of information on these issues as well.